Searchable abstracts of presentations at key conferences in endocrinology

ea0032p603 | Female reproduction | ECE2013

PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenemia

Mastorakos George , Paltoglou George , Tavernarakis George , Christopoulos Panagiotis , Vlassi Margarita , Gazouli Maria , Deligeoroglou Efthimios , Creatsas George

Objective: To investigate the frequencies of three paraoxonase (PON)1 polymorphisms in Greek polycystic ovary syndrome (PCOS) and non-PCOS women, and their genotypes in association with hyperandrogenemia and insulin resistance.Design: Case–control genetic association study.Patients: PCOS cases (NIH criteria) and 112 controls.Main outcome measure: Genotyping of the c.−108C>T (PON1-108), the c.16...